Basic Information
VIS ID
TVIS20001323
Fusion event
HPV-LY86-AS1 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Not given
Quality evaluation
Normal
Reported year
2015
PubMed ID
25581428
Virus Sequence
Virus name
HPV
Reference genome
NC_001526.2;HQ537777.1
Host Sequence
Chromosome
chr6
Cytoband
p25.1
Reference genome
GRCh37/hg19
Start
6503263/6503030 (Hg38)
End
6503263/6503030 (Hg38)
Location type
Intronic
Fragile sites / regions
FRA6B
Target gene
LY86-AS1
Nearest miRNA
hsa-mir-3691/Upstream/333595; hsa-mir-10398/Downstream/3936687;
Nearest TSS
ENST00000381078/Upstream/10046; ENST00000230568/Downstream/84163;
Nearest CpG islands
None/Target, chr6-CpG: 120/Upstream/444599, chr6-CpG: 72/Downstream/43107
Upstream sequence
CTTATGTTTTAAATGTTTGAAATTTTTCATCATGAGAATTTGAGAAAAAAATAATTCTTGTAAGTCTGGTACAGAACAACTGCTATCTTCAAGAAGACGT
Downstream sequence
TCTACCAGCCTCACTCACCATATATAAATTCCTACTAAAAAAAATAGTCTTCTGATATTGCCATTTATACACCAGCCAAAGGCAGGTTGGTATTGAACTT
Reference
Hu, Z., et al. Genome-wide profiling of HPV integration in cervical cancer identifies clustered genomic hot spots and a potential microhomology-mediated integration mechanism. Nat Genet,2015, 47(2): 158-163.
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