Basic Information
VIS ID
TVIS20001367
Fusion event
HPV-LINC00535 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Not given
Quality evaluation
Normal
Reported year
2015
PubMed ID
25581428
Virus Sequence
Virus name
HPV
Reference genome
NC_001526.2;HQ537777.1
Host Sequence
Chromosome
chr8
Cytoband
q22.1
Reference genome
GRCh37/hg19
Start
94516970/93504742 (Hg38)
End
94516970/93504742 (Hg38)
Location type
Intronic
Fragile sites / regions
FRA8B
Target gene
LINC00535
Nearest miRNA
hsa-mir-12123/Upstream/474903; hsa-mir-10400/Downstream/411280;
Nearest TSS
ENST00000518652/Upstream/83862; ENST00000520955/Downstream/193819;
Nearest CpG islands
None/Target, chr8-CpG: 109/Upstream/538501, chr8-CpG: 100/Downstream/195396
Upstream sequence
CTTTGAAACCAACCCAAATCTGGAGAAGATAGAGCAAATAAATTTAACATCTCATTTAGAGGGAATAACACAGCAAAGGTTCCTGCTTAGGCATTGGAAG
Downstream sequence
TGCAAGTGCCCtatttaatttgtccactgaggtatctgtctctcctactatagtgtaaacaccttggaggcaggtctcatgtgttttcatctaggtagtc
Reference
Hu, Z., et al. Genome-wide profiling of HPV integration in cervical cancer identifies clustered genomic hot spots and a potential microhomology-mediated integration mechanism. Nat Genet,2015, 47(2): 158-163.
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