Basic Information
VIS ID
TVIS20001381
Fusion event
HPV-LOC107987116 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Not given
Quality evaluation
Normal
Reported year
2015
PubMed ID
25581428
Virus Sequence
Virus name
HPV
Reference genome
NC_001526.2;HQ537777.1
Host Sequence
Chromosome
chr9
Cytoband
q31.3
Reference genome
GRCh37/hg19
Start
114390494/111628214 (Hg38)
End
114390494/111628214 (Hg38)
Location type
Intronic
Fragile sites / regions
FRA9E
Target gene
LOC107987116
Nearest miRNA
hsa-let-7a-1/Upstream/357000; hsa-mir-12126/Downstream/303886;
Nearest TSS
ENST00000422679/Upstream/28359; ENST00000463589/Downstream/3138;
Nearest CpG islands
None/Target, chr9-CpG: 64/Upstream/143710, chr9-CpG: 84/Downstream/2852
Upstream sequence
caagGGCAACAACTAGATTTGAAACTCCTTTAAAATTTTCAGTTGTTACAAATGCTTGTTATTATTATTGAGATTAATGCTTCTGGTAATTAAACTTTCT
Downstream sequence
ggttgttctttgttttgagatggggtttcgctctgtcgcctaggccagagtgcagtggcatgatcatagctcactgcagcctcaaactgctgggtcaagt
Reference
Hu, Z., et al. Genome-wide profiling of HPV integration in cervical cancer identifies clustered genomic hot spots and a potential microhomology-mediated integration mechanism. Nat Genet,2015, 47(2): 158-163.
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