Basic Information
VIS ID
TVIS20001407
Fusion event
HPV-PLAC1 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Not given
Quality evaluation
Normal
Reported year
2015
PubMed ID
25581428
Virus Sequence
Virus name
HPV
Reference genome
NC_001526.2;HQ537777.1
Host Sequence
Chromosome
chrX
Cytoband
q26.3
Reference genome
GRCh37/hg19
Start
133707490/134573460 (Hg38)
End
133707490/134573460 (Hg38)
Location type
Intronic
Target gene
PLAC1
Nearest miRNA
hsa-let-7f-2/Upstream/26749; hsa-mir-105-1/Downstream/1977418;
Nearest TSS
ENST00000429181/Upstream/23436; ENST00000440614/Downstream/25997;
Nearest CpG islands
None/Target, chrX-CpG: 62/Upstream/22027, chrX-CpG: 53/Downstream/223297
Upstream sequence
GTCTGGTACAGCAGCAGACGGAGCCATCTCCCGGGGCTTTCTGGCTTCTCCGAGGGTGTTCAGGAGTCTCCCAAGTGCGCAGGGGCTCGTGCCCAAAGGG
Downstream sequence
CCATTAGTAGTCTCTGGGAGTCTGCCAAAACCAGATAAAGGCCCATTTGCCTGAGGTGATCTGAAATCATCAGAAGGCAGAGGATTGAATCAGATGTTCC
Reference
Hu, Z., et al. Genome-wide profiling of HPV integration in cervical cancer identifies clustered genomic hot spots and a potential microhomology-mediated integration mechanism. Nat Genet,2015, 47(2): 158-163.
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