Basic Information
VIS ID
TVIS20001432
Fusion event
HPV-MIR181A1HG integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Not given
Quality evaluation
Normal
Reported year
2015
PubMed ID
25581428
Virus Sequence
Virus name
HPV
Subtype
HPV16
Reference genome
NC_001526.2
Host Sequence
Chromosome
chr1
Cytoband
q32.1
Reference genome
GRCh37/hg19
Start
198899060/198929931 (Hg38)
End
198899060/198929931 (Hg38)
Location type
Intronic
Target gene
MIR181A1HG
Nearest miRNA
hsa-mir-101-1/Upstream/70778; hsa-mir-1182/Downstream/2789577;
Nearest TSS
ENST00000473358/Upstream/102715; ENST00000422480/Downstream/7479;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/770697, chr1-CpG: 36/Downstream/1105415
Upstream sequence
AGTTGTTAATAAAAAAAGAAAATGCTTAAACAGTTCGCAATATTATGTATTCAGATTTCTTTGGAAGATTATAAAATATGGTACCATTTGTTTTTCAAAG
Downstream sequence
TGGGACAGGTGGCCACTTTGTCTCATGTATGAGATACTGTTATGTGTGCAATAATTCAAGAGCAAAGTAGATCTAGAACACAGATCTCTTTAATCGTAGG
Reference
Hu, Z., et al. Genome-wide profiling of HPV integration in cervical cancer identifies clustered genomic hot spots and a potential microhomology-mediated integration mechanism. Nat Genet,2015, 47(2): 158-163.
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