Basic Information
VIS ID
TVIS20001439
Fusion event
HPV-LOC105372926 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Not given
Quality evaluation
Normal
Reported year
2015
PubMed ID
25581428
Virus Sequence
Virus name
HPV
Subtype
HPV16
Reference genome
NC_001526.2
Host Sequence
Chromosome
chr1
Cytoband
q41
Reference genome
GRCh37/hg19
Start
219928708/219755366 (Hg38)
End
219928708/219755366 (Hg38)
Location type
Intronic
Target gene
LOC105372926
Nearest miRNA
hsa-mir-101-1/Upstream/7677681; hsa-mir-1182/Downstream/362487;
Nearest TSS
ENST00000473358/Upstream/142221; ENST00000490891/Downstream/163664;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/142146, chr1-CpG: 116/Downstream/172424
Upstream sequence
AAGTCTGAAAAAATCCCTCAAGAATGTTCTACAAAATCCTTGGAGATATACCAGCACACATAGCTTTCCTCAATCACCCAGTCTGTACCACTCATTTTAG
Downstream sequence
CCCCTGTTCATATACTTCCTTGTACCATTTTTCAGTGTGTATTTCTTGTACCCTCAGTAAAACTAAGCTACTGTCACTGAAACCATGCTTTATATTTCTC
Reference
Hu, Z., et al. Genome-wide profiling of HPV integration in cervical cancer identifies clustered genomic hot spots and a potential microhomology-mediated integration mechanism. Nat Genet,2015, 47(2): 158-163.
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