Basic Information
VIS ID
TVIS20001444
Fusion event
HPV-chr1:q43 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Not given
Quality evaluation
Normal
Reported year
2015
PubMed ID
25581428
Virus Sequence
Virus name
HPV
Subtype
HPV16
Reference genome
NC_001526.2
Host Sequence
Chromosome
chr1
Cytoband
q43
Reference genome
GRCh37/hg19
Start
238436836/238273536 (Hg38)
End
238436836/238273536 (Hg38)
Nearest miRNA
hsa-mir-101-1/Upstream/802345; hsa-mir-3123/Downstream/2858736;
Nearest TSS
ENST00000473358/Upstream/328261; ENST00000422844/Downstream/2501;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/489388, chr1-CpG: 91/Downstream/1113419
Upstream sequence
AATTTCAAATTATTTGATACAGTTTACACCCTGATATTCTTATTGGCATAGTCTCCTCTTTTCATACTTGTCTTTTATTTTTCTAGTCCAACATTTGCTG
Downstream sequence
AAGGAGAAGTTAGTTCCTTTAAGTTAAAACAGTAATTTCCCTACAGGAAATATACCGAATCAAGTATAAACCACAAGAATGAGTCGAGCATCTACTTCAA
Reference
Hu, Z., et al. Genome-wide profiling of HPV integration in cervical cancer identifies clustered genomic hot spots and a potential microhomology-mediated integration mechanism. Nat Genet,2015, 47(2): 158-163.
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