Basic Information
VIS ID
TVIS20001448
Fusion event
HPV-LINC02660 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Not given
Quality evaluation
Normal
Reported year
2015
PubMed ID
25581428
Virus Sequence
Virus name
HPV
Subtype
HPV16
Reference genome
NC_001526.2
Host Sequence
Chromosome
chr10
Cytoband
p15.1
Reference genome
GRCh37/hg19
Start
3973053/3930861 (Hg38)
End
3973053/3930861 (Hg38)
Location type
Intronic
Target gene
LINC02660
Nearest miRNA
hsa-mir-5699/Upstream/1854772; hsa-mir-107/Downstream/60299;
Nearest TSS
ENST00000439456/Upstream/96911; ENST00000432452/Downstream/3658;
Nearest CpG islands
None/Target, chr10-CpG: 68/Upstream/144927, chr10-CpG: 60/Downstream/895072
Upstream sequence
CAAGACACAAAAGAATCATCTGACTTTGGCTTGCTGGTTGTGTGACTAACTTTGAGAAGTGTACAATCACCTCTAAAAATGGCTTGCAGAGTGTTGCAGG
Downstream sequence
ATTCCTATTTCTTTTGAATGGTGTGAAACACAGCCAAGCCTCTTACCCTCTCAGCACCAGTTCAAGCACCAGCCCACCAGTATTTCTTTACTACACATAG
Reference
Hu, Z., et al. Genome-wide profiling of HPV integration in cervical cancer identifies clustered genomic hot spots and a potential microhomology-mediated integration mechanism. Nat Genet,2015, 47(2): 158-163.
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