Basic Information
VIS ID
TVIS20001503
Fusion event
HPV-PKP2 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Disease
Not given
Quality evaluation
Normal
Reported year
2015
PubMed ID
Virus Sequence
Virus name
HPV
Subtype
HPV16
Reference genome
Host Sequence
Chromosome
chr12
Cytoband
p11.21
Reference genome
End
33046294/32893360 (Hg38)
Location type
Intronic
Target gene
miRNAs that regulate target gene
Nearest miRNA
hsa-mir-1244-3/Upstream/7019281; hsa-let-7i/Downstream/9430340;
Upstream sequence
AATTGAAAAAACAAAAAAAATACAGAACTAAAAATTAGCATCATTCTTTCTTGCCCTAATTCTAGGGAATTTTTGCAATACAATGAAAGCCAGTCTATTT
Downstream sequence
GTGTCTAACTTCCATGAAACATTTCTTCTACTTCCATTTTTATATCTGCTCTTATTTACCCATCACTTTCTTTCTCTCCTATTACCCAAAATATATTTAA
Reference
Hu, Z., et al. Genome-wide profiling of HPV integration in cervical cancer identifies clustered genomic hot spots and a potential microhomology-mediated integration mechanism. Nat Genet,2015, 47(2): 158-163.
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