Basic Information
VIS ID
TVIS20001522
Fusion event
HPV-LOC105370115 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Not given
Quality evaluation
Normal
Reported year
2015
PubMed ID
25581428
Virus Sequence
Virus name
HPV
Subtype
HPV16
Reference genome
NC_001526.2
Host Sequence
Chromosome
chr13
Cytoband
q12.12
Reference genome
GRCh37/hg19
Start
24529775/23955636 (Hg38)
End
24529775/23955636 (Hg38)
Location type
Intronic
Target gene
LOC105370115
Nearest miRNA
hsa-mir-4499/Upstream/3521790; hsa-mir-1267/Downstream/206780;
Nearest TSS
ENST00000623511/Upstream/52981; ENST00000439928/Downstream/24064;
Nearest CpG islands
None/Target, chr13-CpG: 551/Upstream/51722, chr13-CpG: 28/Downstream/23901
Upstream sequence
ATCCTGAGAAACACGACTCCAAACCCTGTCAGCTGGTTCTAACTGTGCTCACTCTTATAAACAGGTAATAAAATATGGGAAAGAAGGCGATTGCAGACAG
Downstream sequence
GGGACCTCTCCTCCACAGAGACGTGTCCACCAGGAGACTGAGGCAAATCCTATGGGTTCAAAACCGAAGTTTCACTGGCGGCTGAAAACACCCAGGGAAT
Reference
Hu, Z., et al. Genome-wide profiling of HPV integration in cervical cancer identifies clustered genomic hot spots and a potential microhomology-mediated integration mechanism. Nat Genet,2015, 47(2): 158-163.
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