Basic Information
VIS ID
TVIS20001537
Fusion event
HPV-ATP11AUN integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Not given
Quality evaluation
Normal
Reported year
2015
PubMed ID
25581428
Virus Sequence
Virus name
HPV
Subtype
HPV16
Reference genome
NC_001526.2
Host Sequence
Chromosome
chr13
Cytoband
q34
Reference genome
GRCh37/hg19
Start
113336165/112681851 (Hg38)
End
113336165/112681851 (Hg38)
Location type
Intronic
Target gene
ATP11AUN
Nearest miRNA
hsa-mir-1267/Upstream/2340822; hsa-mir-4502/Downstream/581069;
Nearest TSS
ENST00000623511/Upstream/34807; ENST00000419448/Downstream/7964;
Nearest CpG islands
None/Target, chr13-CpG: 551/Upstream/32625, chr13-CpG: 140/Downstream/7688
Upstream sequence
TTATTGCCTTCTAAGAATGTATTGCTCAGTGTAATAAACTTATTAACTAGAAGAATTTGTGATAAGACCAAAGTTATGTCCACCAAAATCAACCCTTGAC
Downstream sequence
ATGCATACACACAGACATTCACAATTAAGTATGATTAATTGCAAGGCAATTACGTCATTTTATTTCTATCATTTTACTTCTATATCATCTTTGACATGTT
Reference
Hu, Z., et al. Genome-wide profiling of HPV integration in cervical cancer identifies clustered genomic hot spots and a potential microhomology-mediated integration mechanism. Nat Genet,2015, 47(2): 158-163.
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