Basic Information
VIS ID
TVIS20001560
Fusion event
HPV-PPP1R14D integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Not given
Quality evaluation
Normal
Reported year
2015
PubMed ID
25581428
Virus Sequence
Virus name
HPV
Subtype
HPV16
Reference genome
NC_001526.2
Host Sequence
Chromosome
chr15
Cytoband
q15.1
Reference genome
GRCh37/hg19
Start
41113180/40820982 (Hg38)
End
41113180/40820982 (Hg38)
Location type
Intronic
Target gene
PPP1R14D
Nearest miRNA
hsa-mir-1233-1/Upstream/3848081; hsa-mir-10393/Downstream/870603;
Nearest TSS
ENST00000557528/Upstream/7319; ENST00000568823/Downstream/7727;
Nearest CpG islands
None/Target, chr15-CpG: 55/Upstream/13302, chr15-CpG: 147/Downstream/22539
Upstream sequence
aattatcaagaattatactcaaaaacactatagggaaatcaaaatggaatgagaaacgtgtttacgtaacctggagaaaggcaaacaaaacaaaataaca
Downstream sequence
tgagaccagcctgagcaacatagcaagaactcttctccattaaaaaaaaaataagaagaaaaaaaaagaaccaggccgggtgccgtggctcacgcctgta
Reference
Hu, Z., et al. Genome-wide profiling of HPV integration in cervical cancer identifies clustered genomic hot spots and a potential microhomology-mediated integration mechanism. Nat Genet,2015, 47(2): 158-163.
Curate