Basic Information
VIS ID
TVIS20001563
Fusion event
HPV-TCF12 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Not given
Quality evaluation
Normal
Reported year
2015
PubMed ID
25581428
Virus Sequence
Virus name
HPV
Subtype
HPV16
Reference genome
NC_001526.2
Host Sequence
Chromosome
chr15
Cytoband
q21.3
Reference genome
GRCh37/hg19
Start
57346037/57053839 (Hg38)
End
57346037/57053839 (Hg38)
Location type
Intronic
Target gene
TCF12
miRNAs that regulate target gene
hsa-mir-204-5p ; hsa-mir-211-5p ; hsa-mir-375 ; hsa-mir-155-5p ; hsa-mir-26b-5p ; hsa-mir-1224-3p ; hsa-mir-548v ; hsa-mir-33a-3p ; hsa-mir-139-5p ; hsa-mir-8485
Nearest miRNA
hsa-mir-10393/Upstream/1680805; hsa-mir-11181/Downstream/2117344;
Nearest TSS
ENST00000557528/Upstream/134322; ENST00000569880/Downstream/9909;
Nearest CpG islands
None/Target, chr15-CpG: 55/Upstream/134032, chr15-CpG: 58/Downstream/252501
Upstream sequence
aaaacacgtgcccagtaacagcatctccaccaatgaactgacaactctggctttgagctctggaaccaatgaactctgtttccaagcagtttctgtgagc
Downstream sequence
ATATTTTATGACGAGGACGGCTTTGATGACCTGAAAGAGTTTAGTTTTATCCTGTAAACAAATGTTTGCTGAGAGCCTGCTGGGTGTGTGGCATTTGGTT
Reference
Hu, Z., et al. Genome-wide profiling of HPV integration in cervical cancer identifies clustered genomic hot spots and a potential microhomology-mediated integration mechanism. Nat Genet,2015, 47(2): 158-163.
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