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TVIS20001579
Basic Information
VIS ID
TVIS20001579
Fusion event
HPV-IGF1R integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Not given
Quality evaluation
Normal
Reported year
2015
PubMed ID
25581428
Virus Sequence
Virus name
HPV
Subtype
HPV16
Reference genome
NC_001526.2
Host Sequence
Chromosome
chr15
Cytoband
q26.3
Reference genome
GRCh37/hg19
Start
99349120/98805891 (Hg38)
End
99349120/98805891 (Hg38)
Location type
Intronic
Target gene
IGF1R
miRNAs that regulate target gene
hsa-mir-122-5p
;
hsa-mir-133b
;
hsa-mir-145-5p
;
hsa-mir-7-5p
;
hsa-mir-138-5p
;
hsa-mir-194-5p
;
hsa-mir-99a-5p
;
hsa-mir-223-3p
;
hsa-mir-100-5p
;
hsa-mir-497-5p
;
hsa-mir-152-3p
;
hsa-mir-139-5p
;
hsa-mir-376c-3p
;
hsa-mir-376a-3p
;
hsa-mir-181b-5p
;
hsa-mir-383-5p
;
hsa-mir-335-5p
;
hsa-mir-215-5p
;
hsa-mir-183-5p
;
hsa-mir-182-5p
;
hsa-mir-196a-5p
;
hsa-mir-192-5p
;
hsa-mir-30a-5p
;
hsa-let-7d-5p
;
hsa-mir-1226-3p
;
hsa-mir-484
;
hsa-mir-320a
;
hsa-mir-34a-5p
;
hsa-mir-92a-3p
;
hsa-let-7e-5p
;
hsa-mir-125b-2-3p
;
hsa-let-7c-5p
;
hsa-mir-16-5p
;
hsa-mir-630
;
hsa-let-7b-5p
;
hsa-mir-143-3p
;
hsa-mir-133a-3p
;
hsa-mir-140-5p
;
hsa-mir-150-3p
;
hsa-mir-375
;
hsa-mir-511-3p
;
hsa-mir-548n
;
hsa-mir-548t-5p
;
hsa-mir-3609
;
hsa-mir-548ah-5p
;
hsa-mir-548at-5p
;
hsa-mir-548az-5p
;
hsa-let-7a-2-3p
;
hsa-let-7g-3p
;
hsa-mir-503-5p
;
hsa-mir-4670-3p
;
hsa-mir-583
;
hsa-mir-885-5p
;
hsa-mir-4668-5p
;
hsa-mir-6124
;
hsa-mir-7151-5p
;
hsa-let-7a-5p
;
hsa-let-7f-5p
;
hsa-mir-33a-3p
;
hsa-mir-98-5p
;
hsa-let-7g-5p
;
hsa-let-7i-5p
;
hsa-mir-577
;
hsa-mir-1294
;
hsa-mir-3927-3p
;
hsa-mir-3935
;
hsa-mir-4458
;
hsa-mir-4500
;
hsa-mir-5586-3p
;
hsa-mir-6740-5p
;
hsa-mir-6831-5p
;
hsa-mir-1275
;
hsa-mir-4665-5p
;
hsa-mir-3919
;
hsa-mir-8485
;
hsa-mir-625-5p
;
hsa-mir-3148
;
hsa-mir-4641
;
hsa-mir-4710
;
hsa-mir-4792
;
hsa-mir-302a-3p
;
hsa-mir-302b-3p
;
hsa-mir-302c-3p
;
hsa-mir-302d-3p
;
hsa-mir-372-3p
;
hsa-mir-373-3p
;
hsa-mir-520e
;
hsa-mir-520a-3p
;
hsa-mir-520b
;
hsa-mir-520c-3p
;
hsa-mir-520d-3p
;
hsa-mir-1253
;
hsa-mir-302e
;
hsa-mir-4299
;
hsa-mir-3646
;
hsa-mir-3662
;
hsa-mir-6770-5p
;
hsa-mir-7855-5p
;
hsa-mir-99b-5p
;
hsa-mir-378a-3p
;
hsa-mir-224-3p
;
hsa-mir-522-3p
;
hsa-mir-1468-3p
;
hsa-mir-885-3p
;
hsa-mir-3613-3p
;
hsa-mir-190a-3p
;
hsa-mir-1277-5p
;
hsa-mir-5011-5p
;
hsa-mir-548d-3p
;
hsa-mir-548h-3p
;
hsa-mir-548z
;
hsa-mir-548ac
;
hsa-mir-548as-3p
;
hsa-mir-548bb-3p
;
hsa-mir-5681a
;
hsa-mir-34a-3p
;
hsa-mir-539-5p
;
hsa-mir-1827
;
hsa-mir-1910-3p
;
hsa-mir-3617-3p
;
hsa-mir-6511a-5p
;
hsa-mir-8060
;
hsa-mir-96-5p
;
hsa-mir-1271-5p
;
hsa-mir-3125
;
hsa-mir-3916
;
hsa-mir-6859-5p
;
hsa-mir-592
;
hsa-mir-597-5p
;
hsa-mir-520a-5p
;
hsa-mir-525-5p
;
hsa-mir-2467-3p
;
hsa-mir-185-5p
;
hsa-mir-206
;
hsa-mir-21-5p
;
hsa-mir-26b-5p
;
hsa-mir-486-5p
;
hsa-mir-218-5p
;
hsa-mir-4535
;
hsa-mir-4800-5p
;
hsa-mir-8071
;
hsa-mir-6745
;
hsa-mir-363-5p
;
hsa-mir-8085
;
hsa-mir-3175
;
hsa-mir-6731-5p
;
hsa-mir-659-5p
;
hsa-mir-492
;
hsa-mir-6861-3p
;
hsa-mir-6804-5p
;
hsa-mir-5572
;
hsa-mir-4260
;
hsa-mir-450a-2-3p
;
hsa-mir-6803-5p
;
hsa-mir-6751-5p
;
hsa-mir-7109-5p
;
hsa-mir-4789-5p
;
hsa-mir-466
;
hsa-mir-5010-5p
;
hsa-mir-4525
;
hsa-mir-7111-5p
;
hsa-mir-6870-5p
;
hsa-mir-5698
;
hsa-mir-4723-5p
;
hsa-mir-202-3p
;
hsa-mir-3163
;
hsa-mir-4643
;
hsa-mir-4789-3p
;
hsa-mir-340-5p
;
hsa-mir-4539
;
hsa-mir-3200-5p
;
hsa-mir-7161-5p
;
hsa-mir-548u
;
hsa-mir-3191-5p
;
hsa-mir-6873-3p
;
hsa-mir-7978
;
hsa-mir-494-3p
;
hsa-mir-4456
;
hsa-mir-548q
;
hsa-mir-6824-3p
;
hsa-mir-6764-3p
;
hsa-mir-518c-5p
;
hsa-mir-6817-3p
;
hsa-mir-7110-3p
;
hsa-mir-4423-3p
;
hsa-mir-449c-5p
;
hsa-mir-34b-5p
;
hsa-mir-2682-5p
;
hsa-mir-940
;
hsa-mir-6893-5p
;
hsa-mir-6808-5p
;
hsa-mir-551b-5p
;
hsa-mir-548c-3p
;
hsa-mir-675-3p
;
hsa-mir-223-5p
;
hsa-mir-7157-5p
;
hsa-mir-4310
;
hsa-mir-4655-5p
;
hsa-mir-224-5p
;
hsa-mir-502-5p
;
hsa-mir-3941
;
hsa-mir-3124-3p
;
hsa-mir-603
;
hsa-mir-362-3p
;
hsa-mir-329-3p
;
hsa-mir-4433b-5p
;
hsa-mir-203a-3p
;
hsa-mir-6794-3p
;
hsa-mir-377-3p
;
hsa-mir-4433a-5p
;
hsa-mir-342-3p
;
hsa-mir-6884-3p
;
hsa-mir-4639-3p
;
hsa-mir-4511
;
hsa-mir-629-3p
;
hsa-mir-3180-5p
;
hsa-mir-488-5p
;
hsa-mir-7161-3p
;
hsa-mir-6738-3p
;
hsa-mir-544a
;
hsa-mir-5001-3p
;
hsa-mir-4727-5p
;
hsa-mir-570-3p
;
hsa-mir-125b-1-3p
;
hsa-mir-588
;
hsa-mir-4701-5p
;
hsa-mir-6727-5p
;
hsa-mir-6084
;
hsa-mir-6762-3p
;
hsa-mir-4755-3p
;
hsa-mir-6774-5p
;
hsa-mir-635
;
hsa-mir-4508
;
hsa-mir-6775-5p
;
hsa-mir-5090
;
hsa-mir-10b-3p
;
hsa-mir-6867-5p
;
hsa-mir-5003-5p
;
hsa-mir-15b-3p
;
hsa-mir-7-1-3p
;
hsa-mir-125b-5p
;
hsa-mir-141-3p
;
hsa-mir-214-5p
;
hsa-mir-448
;
hsa-mir-217
Nearest miRNA
hsa-mir-10393/Upstream/21389; hsa-mir-1302-10/Downstream/3154568;
Nearest TSS
ENST00000557528/Upstream/71179;
ENST00000560277/Downstream/14975;
Nearest CpG islands
None/Target,
chr15-CpG: 55/Upstream/98102
,
chr15-CpG: 47/Downstream/46314
Nearest cancer related gene
IGF1R
(OG, No orient, 0)
Upstream sequence
aagtcaatcaaccttcctgtacctcagtttcttcatttgtaaagtgaagatggtagcagcacctgcatgggttgttgaggataaaataggttcatatatg
Downstream sequence
tgcagttctgacactcaccacctggagttagcacagactccacagggatgagggttcagtcccacgagtctgcccttgctgcagatgcgagtagcaggta
Reference
Hu, Z., et al. Genome-wide profiling of HPV integration in cervical cancer identifies clustered genomic hot spots and a potential microhomology-mediated integration mechanism. Nat Genet,2015, 47(2): 158-163.
Sample Information
×
Sample name
T1804
Sample type
Tumor
Gender
Female
CpG Island Information
×
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