Proximate region of VIS (GRCh38)VISEnhancerEnhancer/PromoterPromoterGene5725892757092537571483675715246657186116571412265714628157132022571366165714628757149759571367195713903257168833571701795713034957131626571270295712816057139801571407995712870257129250571678015716825857167000571672015715960957159778571507295715087857175732
Basic Information
VIS ID
TVIS20001591
Fusion event
HPV-FAM192A integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Not given
Quality evaluation
Normal
Reported year
2015
PubMed ID
25581428
Virus Sequence
Virus name
HPV
Subtype
HPV16
Reference genome
NC_001526.2
Host Sequence
Chromosome
chr16
Cytoband
q13
Reference genome
GRCh37/hg19
Start
57209644/57175732 (Hg38)
End
57209644/57175732 (Hg38)
Location type
Intronic
Target gene
FAM192A
miRNAs that regulate target gene
hsa-mir-186-5p ; hsa-mir-4279 ; hsa-mir-6783-3p ; hsa-mir-1343-3p ; hsa-mir-3194-5p ; hsa-mir-1976 ; hsa-mir-3653-5p ; hsa-mir-26a-2-3p ; hsa-mir-26a-1-3p ; hsa-mir-6742-3p ; hsa-mir-6852-5p ; hsa-mir-939-3p ; hsa-mir-6858-3p ; hsa-mir-181d-5p ; hsa-mir-181c-5p ; hsa-mir-181a-5p ; hsa-mir-181b-5p
Nearest miRNA
hsa-mir-1225/Upstream/271379; hsa-mir-11401/Downstream/596557;
Nearest TSS
ENST00000527434/Upstream/42; ENST00000566352/Downstream/2825;
Nearest CpG islands
None/Target, chr16-CpG: 29/Upstream/82548, chr16-CpG: 87/Downstream/9842
Upstream sequence
acggggtctcccgctgttcctaggctggtcttgaattcctgagctcaattgatcctcccacctaggcctctcaaagtgctgggattacaggtgtgagcca
Downstream sequence
taccatactCCTCCCCAGAAAACACTAAATCTTAGTTGAAAACAAAGACATGTCGACTTCAGCTTTCTTCCTACTTCAAATTCCAGTGCTGAGAATATTC
Reference
Hu, Z., et al. Genome-wide profiling of HPV integration in cervical cancer identifies clustered genomic hot spots and a potential microhomology-mediated integration mechanism. Nat Genet,2015, 47(2): 158-163.
Curate