Basic Information
VIS ID
TVIS20001619
Fusion event
HPV-LINC01601 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Not given
Quality evaluation
Normal
Reported year
2015
PubMed ID
25581428
Virus Sequence
Virus name
HPV
Subtype
HPV16
Reference genome
NC_001526.2
Host Sequence
Chromosome
chr18
Cytoband
q12.3
Reference genome
GRCh37/hg19
Start
42128035/44548070 (Hg38)
End
42128035/44548070 (Hg38)
Location type
Intronic
Target gene
LINC01601
Nearest miRNA
hsa-mir-1-2/Upstream/4871291; hsa-mir-122/Downstream/422012;
Nearest TSS
ENST00000575820/Upstream/16373; ENST00000591940/Downstream/131647;
Nearest CpG islands
None/Target, chr18-CpG: 67/Upstream/4706205, chr18-CpG: 180/Downstream/130948
Upstream sequence
GGACAAGCATCCACAACTGTAGGGTCAGGGCCCAATTCTGCTGGCTTGGGTTCTGATGACCCTTTCACCTTTGCAATTCTGTGTCCTGCCTGCTAGATCC
Downstream sequence
CACATTGTTGGTTTTGGAAAATCATCAATTTATAAATGCAATATCCCTTTCTTCTCAATAAGGGTCATTTTACAAATGGAAAATGTCAAAATTCTTATGG
Reference
Hu, Z., et al. Genome-wide profiling of HPV integration in cervical cancer identifies clustered genomic hot spots and a potential microhomology-mediated integration mechanism. Nat Genet,2015, 47(2): 158-163.
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