Basic Information
VIS ID
TVIS20001643
Fusion event
HPV-MIR3681HG integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Not given
Quality evaluation
Normal
Reported year
2015
PubMed ID
25581428
Virus Sequence
Virus name
HPV
Subtype
HPV16
Reference genome
NC_001526.2
Host Sequence
Chromosome
chr2
Cytoband
p24.3
Reference genome
GRCh37/hg19
Start
12517081/12376955 (Hg38)
End
12517081/12376955 (Hg38)
Location type
Intronic
Target gene
MIR3681HG
Nearest miRNA
hsa-mir-3681/Upstream/177754; hsa-mir-10b/Downstream/360412;
Nearest TSS
ENST00000437798/Upstream/62638; ENST00000414086/Downstream/222032;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/591828, chr2-CpG: 204/Downstream/339544
Upstream sequence
tgagttcaaaacccagcagcgcagtcattaaatcttaaagctctaaaataatttcctttgattccatgtctcacatccagggcacactgatgcaatgggt
Downstream sequence
ttagagaggcccgactccctagcatttgggaattaagatctgagagccatgtgtgttcactgcttctgtgtcatcattgactctaggccctttcagtaga
Reference
Hu, Z., et al. Genome-wide profiling of HPV integration in cervical cancer identifies clustered genomic hot spots and a potential microhomology-mediated integration mechanism. Nat Genet,2015, 47(2): 158-163.
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