Proximate region of VIS (GRCh38)VISEnhancerEnhancer/PromoterPromoterGene6215112561953469620658106204176062044161620251156202677962030342620317996201893262020333620109456201111462003145620032946201432562014474620214256202157462052297
Basic Information
VIS ID
TVIS20001709
Fusion event
HPV-TAF4 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Not given
Quality evaluation
Normal
Reported year
2015
PubMed ID
25581428
Virus Sequence
Virus name
HPV
Subtype
HPV16
Reference genome
NC_001526.2
Host Sequence
Chromosome
chr20
Cytoband
q13.33
Reference genome
GRCh37/hg19
Start
60627353/62052297 (Hg38)
End
60627353/62052297 (Hg38)
Location type
Intronic
Target gene
TAF4
miRNAs that regulate target gene
hsa-mir-19b-3p ; hsa-mir-7-5p ; hsa-mir-93-5p ; hsa-mir-19a-3p
Nearest miRNA
hsa-mir-103a-2/Upstream/98635; hsa-mir-1-1/Downstream/12505;
Nearest TSS
ENST00000382410/Upstream/39414; ENST00000635124/Downstream/12069;
Nearest CpG islands
None/Target, chr20-CpG: 39/Upstream/45491, chr20-CpG: 25/Downstream/944
Upstream sequence
CCAAGCGCAAGCTGGAGGGTGACCTGAAGCTGACGCAGGAGTCGGTGGCTGATGCTGCTCAAGACAAGCAGCAGCTGGAGGAGAAGCTCAAGAAGTAGGT
Downstream sequence
TTTGTTTCCGCTATTGAGCATGGCTCCAAGATCTCTCCTTAAAATACAAACAGGAAAAAACAAAGAAACTGTCCTTTGACCCCCTCACCACAGTCAGTGA
Reference
Hu, Z., et al. Genome-wide profiling of HPV integration in cervical cancer identifies clustered genomic hot spots and a potential microhomology-mediated integration mechanism. Nat Genet,2015, 47(2): 158-163.
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