Basic Information
VIS ID
TVIS20001729
Fusion event
HPV-LOC107985581 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Disease
Not given
Quality evaluation
Normal
Reported year
2015
PubMed ID
Virus Sequence
Virus name
HPV
Subtype
HPV16
Reference genome
Host Sequence
Chromosome
chr22
Cytoband
q13.32
Reference genome
End
48576563/48180751 (Hg38)
Location type
Intronic
Fragile sites / regions
Target gene
Nearest miRNA
hsa-let-7a-3/Upstream/2066983; hsa-mir-12114/Downstream/93613;
Upstream sequence
GGGAAACAAAGCAAAGCCATTTGGTGAAAGGTTTGGGCAGCTGCGATGCGGTGGATGCATCTTTGGGGAGGGGCAGGGGGACCATCCATGTGGGCTTCTG
Downstream sequence
GGGCTGTGGCCTCTCCACGGACAGGAAGCCAGCTGATGCCCTTGCCCTGGAGCTAGGACAACCCAGGCCTTCCTGAGCCTCAGATGCAGGGCAGGGTGCT
Reference
Hu, Z., et al. Genome-wide profiling of HPV integration in cervical cancer identifies clustered genomic hot spots and a potential microhomology-mediated integration mechanism. Nat Genet,2015, 47(2): 158-163.
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