Basic Information
VIS ID
TVIS20001750
Fusion event
HPV-LOC105374039 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Not given
Quality evaluation
Normal
Reported year
2015
PubMed ID
25581428
Virus Sequence
Virus name
HPV
Subtype
HPV16
Reference genome
NC_001526.2
Host Sequence
Chromosome
chr3
Cytoband
q13.13
Reference genome
GRCh37/hg19
Start
111117576/111398729 (Hg38)
End
111117576/111398729 (Hg38)
Location type
Intronic
Target gene
LOC105374039
Nearest miRNA
hsa-let-7g/Upstream/1795832; hsa-mir-12124/Downstream/714072;
Nearest TSS
ENST00000440867/Upstream/106010; ENST00000488054/Downstream/98366;
Nearest CpG islands
None/Target, chr3-CpG: 148/Upstream/326175, chr3-CpG: 21/Downstream/275751
Upstream sequence
CTTCCAAAAGCATGGATGCAGGAGGGAAGCACCAAGGAGAGCAAGTCAAGGTTGGCTGGAGTAGGGGATCTCAgcatgctagagtcaactggggagcatt
Downstream sequence
tttttcttgcccttcagtagtttgaagctgctccactgtctttgacttacattattttcaagcggaaatcgtctgtaatccttactgatcttcatctata
Reference
Hu, Z., et al. Genome-wide profiling of HPV integration in cervical cancer identifies clustered genomic hot spots and a potential microhomology-mediated integration mechanism. Nat Genet,2015, 47(2): 158-163.
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