Basic Information
VIS ID
TVIS20001818
Fusion event
HPV-SLC6A3 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Not given
Quality evaluation
Normal
Reported year
2015
PubMed ID
25581428
Virus Sequence
Virus name
HPV
Subtype
HPV16
Reference genome
NC_001526.2
Host Sequence
Chromosome
chr5
Cytoband
p15.33
Reference genome
GRCh37/hg19
Start
1410899/1410784 (Hg38)
End
1410899/1410784 (Hg38)
Location type
Intronic
Target gene
SLC6A3
miRNAs that regulate target gene
hsa-mir-137 ; hsa-mir-491-5p
Nearest miRNA
hsa-mir-4457/Upstream/101407; hsa-mir-10397/Downstream/99978;
Nearest TSS
ENST00000502646/Upstream/9477; ENST00000605200/Downstream/5794;
Nearest CpG islands
None/Target, chr5-CpG: 87/Upstream/24037, chr5-CpG: 16/Downstream/5893
Upstream sequence
TTAATGAAATAAGCATACTAGGAAATTGATTAATTTCCTGTGTAATACAGCAGGGAATATGACACCAAATGCAGGTGGTAGTTGTAATTAGCTTTtatct
Downstream sequence
CGTGCATGCatgtctgtgtgtatgtgtgtgtgcatgcgtgtgtgcatgtgtgtgttcgtgtgtgttcatgtatgtgtgcgtgtgtgcatgtgtgtatgtg
Reference
Hu, Z., et al. Genome-wide profiling of HPV integration in cervical cancer identifies clustered genomic hot spots and a potential microhomology-mediated integration mechanism. Nat Genet,2015, 47(2): 158-163.
Curate