Basic Information
VIS ID
TVIS20001848
Fusion event
HPV-LOC101927421 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Not given
Quality evaluation
Normal
Reported year
2015
PubMed ID
25581428
Virus Sequence
Virus name
HPV
Subtype
HPV16
Reference genome
NC_001526.2
Host Sequence
Chromosome
chr5
Cytoband
q23.2
Reference genome
GRCh37/hg19
Start
124556874/125221181 (Hg38)
End
124556874/125221181 (Hg38)
Location type
Intronic
Target gene
LOC101927421
Nearest miRNA
hsa-mir-10397/Upstream/6066465; hsa-mir-103a-1/Downstream/3876507;
Nearest TSS
ENST00000502646/Upstream/184543; ENST00000625219/Downstream/104169;
Nearest CpG islands
None/Target, chr5-CpG: 87/Upstream/569126, chr5-CpG: 30/Downstream/1202174
Upstream sequence
CCAAACACTTATGACTCAAATATACATAAATTTTGTTTTTGCTATATTTACCATGTTTCTCTGTATGCTGAAATACCAAACGAGACTTCCAGCCTGGGAA
Downstream sequence
CTTCCAGTGTGGGACTATAGTTACTGAATCTACTGAAATGCTTGTGGGGCACATTCCGTGTTCATGTTCTCCACAATGGTGGTATATCACAAGACAAGTA
Reference
Hu, Z., et al. Genome-wide profiling of HPV integration in cervical cancer identifies clustered genomic hot spots and a potential microhomology-mediated integration mechanism. Nat Genet,2015, 47(2): 158-163.
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