Basic Information
VIS ID
TVIS20001872
Fusion event
HPV-LINC00472 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Not given
Quality evaluation
Normal
Reported year
2015
PubMed ID
25581428
Virus Sequence
Virus name
HPV
Subtype
HPV16
Reference genome
NC_001526.2
Host Sequence
Chromosome
chr6
Cytoband
q13
Reference genome
GRCh37/hg19
Start
72118671/71408968 (Hg38)
End
72118671/71408968 (Hg38)
Location type
Intronic
Fragile sites / regions
FRA6D
Target gene
LINC00472
Nearest miRNA
hsa-mir-10398/Upstream/5347; hsa-mir-10524/Downstream/1558719;
Nearest TSS
ENST00000381078/Upstream/80026; ENST00000431997/Downstream/8468;
Nearest CpG islands
None/Target, chr6-CpG: 120/Upstream/119562, chr6-CpG: 138/Downstream/10837
Upstream sequence
tttcatgcataagtatttcagcgtggatcactgaagataaggattctttacctaaacacaagtgaaacagtcctataacatcttgtaaaaaaaaatgaca
Downstream sequence
ATGCTTTTGCCAAGGTAGGAAGACACATAGCATTAGACTGTTCTGATAGTGACTGGCACAGACAGGTCTCTTAGGCTCATAGACTGTTCTCTCCCTGAAT
Reference
Hu, Z., et al. Genome-wide profiling of HPV integration in cervical cancer identifies clustered genomic hot spots and a potential microhomology-mediated integration mechanism. Nat Genet,2015, 47(2): 158-163.
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