Basic Information
VIS ID
TVIS20001877
Fusion event
HPV-LOC107986638 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Not given
Quality evaluation
Normal
Reported year
2015
PubMed ID
25581428
Virus Sequence
Virus name
HPV
Subtype
HPV16
Reference genome
NC_001526.2
Host Sequence
Chromosome
chr6
Cytoband
q22.1
Reference genome
GRCh37/hg19
Start
114759145/114437981 (Hg38)
End
114759145/114437981 (Hg38)
Location type
Intronic
Fragile sites / regions
FRA6F
Target gene
LOC107986638
Nearest miRNA
hsa-mir-10398/Upstream/7653761; hsa-mir-1202/Downstream/4631066;
Nearest TSS
ENST00000381078/Upstream/12369; ENST00000517965/Downstream/10979;
Nearest CpG islands
None/Target, chr6-CpG: 120/Upstream/94286, chr6-CpG: 74/Downstream/1662529
Upstream sequence
gaataacaaacacctaacatcatgatgaagatcaaattcataaatactaatatctacctaaaatcatgatgaagatcaaatgcacaaatatcaatattaa
Downstream sequence
ATAGTGATTGACTTTTGagtggccttcctcaaagcatggtctgaagaccactgcatcaggatcaccagagcctcttgttgaaaatgtaagttctgggttt
Reference
Hu, Z., et al. Genome-wide profiling of HPV integration in cervical cancer identifies clustered genomic hot spots and a potential microhomology-mediated integration mechanism. Nat Genet,2015, 47(2): 158-163.
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