Basic Information
VIS ID
TVIS20001947
Fusion event
HPV-LOC102724710 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Not given
Quality evaluation
Normal
Reported year
2015
PubMed ID
25581428
Virus Sequence
Virus name
HPV
Subtype
HPV16
Reference genome
NC_001526.2
Host Sequence
Chromosome
chr8
Cytoband
q22.1
Reference genome
GRCh37/hg19
Start
93639741/92627513 (Hg38)
End
93639741/92627513 (Hg38)
Location type
Intronic
Target gene
LOC102724710
Nearest miRNA
hsa-mir-12123/Upstream/1421954; hsa-mir-10400/Downstream/402238;
Nearest TSS
ENST00000518652/Upstream/117697; ENST00000522531/Downstream/27981;
Nearest CpG islands
None/Target, chr8-CpG: 109/Upstream/483101, chr8-CpG: 56/Downstream/338052
Upstream sequence
GTccagcactttgggaggccaaggcaggcggatcacctgaggtcagaagttcaagaccagcctggccaacatggtgaaaccccatctctactaaaaaaac
Downstream sequence
AATTAACTCAAGATTGCTTCCATTAGCCTTTCCTCTTCTCATCCCCCCATCTGCCTGGAGGAAAATGCTTGCTGATGGCACTTCCTGGCACAACAGCAAT
Reference
Hu, Z., et al. Genome-wide profiling of HPV integration in cervical cancer identifies clustered genomic hot spots and a potential microhomology-mediated integration mechanism. Nat Genet,2015, 47(2): 158-163.
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