Basic Information
VIS ID
TVIS20001967
Fusion event
HPV-LOC107987087 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Not given
Quality evaluation
Normal
Reported year
2015
PubMed ID
25581428
Virus Sequence
Virus name
HPV
Subtype
HPV16
Reference genome
NC_001526.2
Host Sequence
Chromosome
chr9
Cytoband
q21.32
Reference genome
GRCh37/hg19
Start
85118005/82503090 (Hg38)
End
85118005/82503090 (Hg38)
Location type
Intronic
Target gene
LOC107987087
Nearest miRNA
hsa-mir-101-2/Upstream/11693006; hsa-let-7a-1/Downstream/1466658;
Nearest TSS
ENST00000422679/Upstream/51434; ENST00000416473/Downstream/560038;
Nearest CpG islands
None/Target, chr9-CpG: 64/Upstream/813004, chr9-CpG: 137/Downstream/559010
Upstream sequence
atgtttcatagacttgatttataaaaataggaagcaggctggatgtggcccatgggccatagttttccaacTTTGGTCTAGactagctttgaaatcttac
Downstream sequence
gcagcagaggatagttctccaaagtaggaggcacaccttgatttgagaggcaacaacctgtttggaatgatagaaatatggtgggcaagctggcagcaga
Reference
Hu, Z., et al. Genome-wide profiling of HPV integration in cervical cancer identifies clustered genomic hot spots and a potential microhomology-mediated integration mechanism. Nat Genet,2015, 47(2): 158-163.
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