Basic Information
VIS ID
TVIS20002004
Fusion event
HPV-FGF13 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Not given
Quality evaluation
Normal
Reported year
2015
PubMed ID
25581428
Virus Sequence
Virus name
HPV
Subtype
HPV16
Reference genome
NC_001526.2
Host Sequence
Chromosome
chrX
Cytoband
q26.3
Reference genome
GRCh37/hg19
Start
137779191/138697029 (Hg38)
End
137779191/138697029 (Hg38)
Location type
Intronic
Target gene
FGF13
Nearest miRNA
hsa-let-7f-2/Upstream/29236; hsa-mir-105-1/Downstream/1227119;
Nearest TSS
ENST00000429181/Upstream/69952; ENST00000446383/Downstream/14423;
Nearest CpG islands
None/Target, chrX-CpG: 62/Upstream/1122103, chrX-CpG: 84/Downstream/13904
Upstream sequence
cttgttcatggccatcatttgctgagcaagcccttccatcggagatgctgtaaaggtaaactgcaattagacccctgacacaatcctcactgactccaaa
Downstream sequence
TGCAATATGTGTTGaaaaattataaaattttaaaaaCCAAGCTAAATGCATTAAATATAACCTAAATATTAACTTAGGCATGTAACATTCTTAAAGGAAA
Reference
Hu, Z., et al. Genome-wide profiling of HPV integration in cervical cancer identifies clustered genomic hot spots and a potential microhomology-mediated integration mechanism. Nat Genet,2015, 47(2): 158-163.
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