Basic Information
VIS ID
TVIS20002015
Fusion event
HPV-RIMBP2 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Disease
Not given
Quality evaluation
Normal
Reported year
2015
PubMed ID
Virus Sequence
Virus name
HPV
Subtype
HPV16
Reference genome
Host Sequence
Chromosome
chr12
Cytoband
q24.33
Reference genome
End
131097817/130613272 (Hg38)
Location type
Intronic
Fragile sites / regions
Target gene
Nearest miRNA
hsa-let-7i/Upstream/2319094; hsa-mir-6763/Downstream/1968725;
Upstream sequence
CTTTTTGGAAATCTCCCCAGTAGGCCTGTCAGAAGCTTTCAGTATGCACCAACATCGGCCCCCACCAGCCAGGCCCCCATTCCTGTGATGAAAGTCCTGT
Downstream sequence
TGAGGGcccacttgacagatgaggaagctgaggctgagCCTTCAGTGCTCAGGCAGGGGGATGCTCTCTGGAGGCCAGAGTATTTTATTCACCACTACAT
Reference
Hu, Z., et al. Genome-wide profiling of HPV integration in cervical cancer identifies clustered genomic hot spots and a potential microhomology-mediated integration mechanism. Nat Genet,2015, 47(2): 158-163.
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