Basic Information
VIS ID
TVIS20002093
Fusion event
HPV-LOC107984536 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Not given
Quality evaluation
Normal
Reported year
2015
PubMed ID
25581428
Virus Sequence
Virus name
HPV
Reference genome
NC_001526.2;AY262282.1
Host Sequence
Chromosome
chr12
Cytoband
q21.31
Reference genome
GRCh37/hg19
Start
84343891/83950112 (Hg38)
End
84343891/83950112 (Hg38)
Location type
Intronic
Fragile sites / regions
FRA12B
Target gene
LOC107984536
Nearest miRNA
hsa-let-7i/Upstream/2791651; hsa-mir-1178/Downstream/2794956;
Nearest TSS
ENST00000382841/Upstream/288393; ENST00000642846/Downstream/204226;
Nearest CpG islands
None/Target, chr12-CpG: 104/Upstream/1262245, chr12-CpG: 17/Downstream/961309
Upstream sequence
CATATGGGGCTATTTGGGTAGCTACCCACATACATACATGAATGTATTTTCATCATTGTTTATTCTACGAAACTAGAATCCTTATTACATACACTTTTGC
Downstream sequence
TACATCTTGCGTGTCTCGTTATAGACATCTCTTGAGCCTTTTAGCATAGATCTAACAGAttatttttctccccgacatgtatgatgaagtgtgttaaaca
Reference
Hu, Z., et al. Genome-wide profiling of HPV integration in cervical cancer identifies clustered genomic hot spots and a potential microhomology-mediated integration mechanism. Nat Genet,2015, 47(2): 158-163.
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