Basic Information
VIS ID
TVIS20002097
Fusion event
HPV-TEKT5 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Not given
Quality evaluation
Normal
Reported year
2015
PubMed ID
25581428
Virus Sequence
Virus name
HPV
Reference genome
NC_001526.2;AY262282.1
Host Sequence
Chromosome
chr16
Cytoband
p13.13
Reference genome
GRCh37/hg19
Start
10742205/10648348 (Hg38)
End
10742205/10648348 (Hg38)
Location type
Intronic
Target gene
TEKT5
Nearest miRNA
hsa-mir-1225/Upstream/5015782; hsa-mir-11401/Downstream/658092;
Nearest TSS
ENST00000527434/Upstream/67650; ENST00000576710/Downstream/23430;
Nearest CpG islands
None/Target, chr16-CpG: 29/Upstream/20558, chr16-CpG: 55/Downstream/95379
Upstream sequence
AGAGAGAATGTATTCATTAAGGAGGTTGAGGAGGAAGGGTGTGAGGTGTGCAATCAGGAGATATGTGGTCACAAAAAGCAAAAAATAAAAAACAACAAAC
Downstream sequence
gctgtgttacccaggctggaatgcagtggagtgatctcggctcactgcaacctccgcctcccagggtcaagtgattctcctgcctcagcctcctgagtag
Reference
Hu, Z., et al. Genome-wide profiling of HPV integration in cervical cancer identifies clustered genomic hot spots and a potential microhomology-mediated integration mechanism. Nat Genet,2015, 47(2): 158-163.
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