Basic Information
VIS ID
TVIS20002098
Fusion event
HPV-DOC2A integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Not given
Quality evaluation
Normal
Reported year
2015
PubMed ID
25581428
Virus Sequence
Virus name
HPV
Reference genome
NC_001526.2;AY262282.1
Host Sequence
Chromosome
chr16
Cytoband
p11.2
Reference genome
GRCh37/hg19
Start
30027701/30016380 (Hg38)
End
30027701/30016380 (Hg38)
Location type
Intronic
Target gene
DOC2A
Nearest miRNA
hsa-mir-1225/Upstream/417115; hsa-mir-11401/Downstream/487539;
Nearest TSS
ENST00000527434/Upstream/4044; ENST00000561910/Downstream/4915;
Nearest CpG islands
None/Target, chr16-CpG: 29/Upstream/4694, chr16-CpG: 30/Downstream/5083
Upstream sequence
catctcattatagaaccaaaccaatcctatgcagaaggttctagcaacattcccTGGCttttatttttatttatcatttttttttttgagacagagtctt
Downstream sequence
TCCTTCGTGGCTCTCCAGAATAAGAAAGGAAGCAGGACGAAGGGAGACACAGTGCAGTGTGAAAGCCGGTGAGTTTAGCAAGAGGGTGTCCATGACCTGG
Reference
Hu, Z., et al. Genome-wide profiling of HPV integration in cervical cancer identifies clustered genomic hot spots and a potential microhomology-mediated integration mechanism. Nat Genet,2015, 47(2): 158-163.
Curate