Basic Information
VIS ID
TVIS20002107
Fusion event
HPV-KANSL1 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Disease
Not given
Quality evaluation
Normal
Reported year
2015
PubMed ID
Virus Sequence
Virus name
HPV
Reference genome
NC_001526.2;AY262282.1
Host Sequence
Chromosome
chr17
Cytoband
q21.31
Reference genome
End
44226764/46149398 (Hg38)
Location type
Intronic
Target gene
miRNAs that regulate target gene
hsa-mir-130b-3p ; hsa-mir-148a-3p ; hsa-mir-106b-5p ; hsa-mir-149-5p ; hsa-mir-23b-3p ; hsa-mir-17-5p ; hsa-mir-154-3p ; hsa-mir-487a-3p ; hsa-mir-513a-3p ; hsa-mir-513c-3p ; hsa-mir-3606-3p ; hsa-mir-130b-5p ; hsa-mir-1287-3p ; hsa-mir-6780a-5p ; hsa-mir-6779-5p ; hsa-mir-3689c ; hsa-mir-3689b-3p ; hsa-mir-3689a-3p ; hsa-mir-30b-3p ; hsa-mir-1273h-5p ; hsa-mir-555 ; hsa-mir-6881-5p ; hsa-mir-6835-5p ; hsa-mir-6825-5p ; hsa-mir-6883-5p ; hsa-mir-6799-5p ; hsa-mir-6785-5p ; hsa-mir-4728-5p ; hsa-mir-149-3p ; hsa-mir-7106-5p ; hsa-mir-6871-5p ; hsa-mir-6732-5p ; hsa-mir-449b-3p ; hsa-mir-5683 ; hsa-mir-4664-3p ; hsa-mir-1180-3p ; hsa-mir-5585-3p ; hsa-mir-1322 ; hsa-mir-1272 ; hsa-mir-548g-3p ; hsa-mir-4282 ; hsa-mir-548f-3p ; hsa-mir-548e-3p ; hsa-mir-548az-3p ; hsa-mir-548ar-3p ; hsa-mir-548a-3p ; hsa-mir-548x-3p ; hsa-mir-548j-3p ; hsa-mir-548aq-3p ; hsa-mir-548am-3p ; hsa-mir-548aj-3p ; hsa-mir-548ah-3p ; hsa-mir-548ae-3p ; hsa-mir-548z ; hsa-mir-548h-3p ; hsa-mir-548d-3p ; hsa-mir-548bb-3p ; hsa-mir-548ac ; hsa-mir-192-3p ; hsa-mir-627-5p ; hsa-mir-127-5p ; hsa-mir-921 ; hsa-mir-3606-5p ; hsa-mir-924 ; hsa-mir-6806-3p ; hsa-mir-3928-5p ; hsa-mir-3174 ; hsa-mir-155-5p ; hsa-mir-365a-3p ; hsa-mir-365b-3p ; hsa-mir-4762-3p ; hsa-mir-4756-3p ; hsa-mir-7855-5p ; hsa-mir-539-3p ; hsa-mir-485-3p ; hsa-mir-4524a-3p ; hsa-mir-4768-3p ; hsa-mir-4700-3p ; hsa-mir-4524b-3p ; hsa-mir-7111-3p ; hsa-mir-6769b-3p ; hsa-mir-4723-3p ; hsa-mir-3183 ; hsa-mir-660-3p ; hsa-mir-5193 ; hsa-mir-3974 ; hsa-mir-384 ; hsa-mir-3685 ; hsa-mir-4753-3p ; hsa-mir-6873-3p ; hsa-mir-7975 ; hsa-mir-5571-3p ; hsa-mir-4789-5p ; hsa-mir-6817-3p ; hsa-mir-7110-3p ; hsa-mir-8067 ; hsa-mir-6508-5p ; hsa-mir-4528 ; hsa-mir-4742-3p ; hsa-mir-548av-3p ; hsa-mir-521 ; hsa-mir-5006-3p ; hsa-mir-4755-5p ; hsa-mir-211-5p ; hsa-mir-204-5p ; hsa-mir-623 ; hsa-mir-6870-3p ; hsa-mir-5088-3p
Nearest miRNA
hsa-mir-1180/Upstream/673963; hsa-mir-10226/Downstream/823619;
Upstream sequence
CCCTAGCACACAGCACAGGGGAAGGAAGGGCTTGGCGTCTAGCCCAGGCCGGCAGTCTGGCCCTGGAGCCGGAGTTCGGGACCACTTTGCCCCATTGCCA
Downstream sequence
GATTTCTGCCTCCACTCCTCTAATCcaggggttggcaaactttttctgtaaagggccagatggcaaatatttaggctttgcaggccacacagtctccgtc
Reference
Hu, Z., et al. Genome-wide profiling of HPV integration in cervical cancer identifies clustered genomic hot spots and a potential microhomology-mediated integration mechanism. Nat Genet,2015, 47(2): 158-163.
Curate