Basic Information
VIS ID
TVIS20002121
Fusion event
HPV-ZFYVE28 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Not given
Quality evaluation
Normal
Reported year
2015
PubMed ID
25581428
Virus Sequence
Virus name
HPV
Reference genome
NC_001526.2;AY262282.1
Host Sequence
Chromosome
chr4
Cytoband
p16.3
Reference genome
GRCh37/hg19
Start
2290004/2288277 (Hg38)
End
2290004/2288277 (Hg38)
Location type
Intronic
Target gene
ZFYVE28
miRNAs that regulate target gene
hsa-mir-335-5p ; hsa-mir-192-5p
Nearest miRNA
hsa-mir-4800/Upstream/38121; hsa-mir-12113/Downstream/3634998;
Nearest TSS
ENST00000502981/Upstream/562; ENST00000510632/Downstream/7307;
Nearest CpG islands
None/Target, chr4-CpG: 46/Upstream/12095, chr4-CpG: 24/Downstream/15510
Upstream sequence
TGACCCATGAAAAGTTATCTAGGCCATACTTAGGGCAAAATCATAAGTTAGGCACAAAGAAGAGGTGTGAACTTCTTGCAttttaaggacttctgaagga
Downstream sequence
CTGTGGCCCCAGAGCTGGCTCCCAGGAAAACCAACAGGTGACACTAGAACGGAACCTCATCTCTAATGAGGGCAAGTCCTGATCTGTGCAGTGAGGGGGT
Reference
Hu, Z., et al. Genome-wide profiling of HPV integration in cervical cancer identifies clustered genomic hot spots and a potential microhomology-mediated integration mechanism. Nat Genet,2015, 47(2): 158-163.
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