Basic Information
VIS ID
TVIS20002166
Fusion event
HPV-MORC2 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Disease
Not given
Quality evaluation
Normal
Reported year
2015
PubMed ID
Virus Sequence
Virus name
HPV
Subtype
HPV16
Reference genome
Host Sequence
Chromosome
chr22
Cytoband
q12.2
Reference genome
End
31332301/30936314 (Hg38)
Location type
Intronic
Fragile sites / regions
Target gene
Nearest miRNA
hsa-mir-1286/Upstream/204673; hsa-let-7a-3/Downstream/223748;
Upstream sequence
TACCTCTAAGGCAGAATTTTTATTTTCTAGAGTTTTATACATTCTAAATGAATTGGACCACTTTGAAGTATATAAGCATTTTTTCTTAAGAATAAGCAAG
Downstream sequence
GTGTTATTCTTAAAATAACACTGTTGGCAAATAGTACACGTGGACCTGGAGGTTGGGGTTGGAAAGCTTTGGCAAACAACGCGGGTGAGTGGAGGGTAAA
Reference
Hu, Z., et al. Genome-wide profiling of HPV integration in cervical cancer identifies clustered genomic hot spots and a potential microhomology-mediated integration mechanism. Nat Genet,2015, 47(2): 158-163.
Curate