Basic Information
VIS ID
TVIS20002184
Fusion event
HPV-LOC105375631 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Not given
Quality evaluation
Normal
Reported year
2015
PubMed ID
25581428
Virus Sequence
Virus name
HPV
Reference genome
NC_001526.2;AY262282.1
Host Sequence
Chromosome
chr8
Cytoband
q21.3
Reference genome
GRCh37/hg19
Start
90383150/89370921 (Hg38)
End
90383150/89370921 (Hg38)
Location type
Intronic
Target gene
LOC105375631
Nearest miRNA
hsa-mir-12123/Upstream/9129448; hsa-mir-10400/Downstream/1834564;
Nearest TSS
ENST00000518652/Upstream/562013; ENST00000517696/Downstream/246236;
Nearest CpG islands
None/Target, chr8-CpG: 109/Upstream/1042669, chr8-CpG: 92/Downstream/386386
Upstream sequence
atttttgtccaatgattttgtgtcccaaaaatttgctaaagttgtttatcagatcaaggaagctttgggcagagactatggggttttctaggtgtggaat
Downstream sequence
tcagtgctcaaaacgttttggattttggagcttttggataagggatgtccaacctAAAATAAGACAGTATCATGAACAACTTACAGCAAATACATTCAAC
Reference
Hu, Z., et al. Genome-wide profiling of HPV integration in cervical cancer identifies clustered genomic hot spots and a potential microhomology-mediated integration mechanism. Nat Genet,2015, 47(2): 158-163.
Curate