Basic Information
VIS ID
TVIS20002223
Fusion event
HPV-CCDC148 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Disease
Not given
Quality evaluation
Normal
Reported year
2015
PubMed ID
Virus Sequence
Virus name
HPV
Subtype
HPV16
Reference genome
Host Sequence
Chromosome
chr2
Cytoband
q24.1
Reference genome
End
159299583/158443071 (Hg38)
Location type
Intronic
Target gene
Nearest miRNA
hsa-mir-128-1/Upstream/7074660; hsa-mir-10b/Downstream/743764;
Upstream sequence
ACACTCCAAACTAACCAGCCCAAGCCCCTATCCAGAATAGAACCCCAGCTGGGAACAGACTCCAAATTGAGCACTTCAGGAAAATAGAGAAAAGCAAAAA
Downstream sequence
AGCTGCTCCCTTGTTAAGGTAGGGGTAAGGTCCTAGAGTTAGGGACAGGAAGGCAAGATATAAGTAGGAGTAAAGGGGAAAGGCATATCTTGAACAAAAA
Reference
Hu, Z., et al. Genome-wide profiling of HPV integration in cervical cancer identifies clustered genomic hot spots and a potential microhomology-mediated integration mechanism. Nat Genet,2015, 47(2): 158-163.
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