Basic Information
VIS ID
TVIS20002245
Fusion event
HPV-LOC107985194 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Not given
Quality evaluation
Normal
Reported year
2015
PubMed ID
25581428
Virus Sequence
Virus name
HPV
Subtype
HPV16
Reference genome
NC_001526.2
Host Sequence
Chromosome
chr1
Cytoband
p11.2
Reference genome
GRCh37/hg19
Start
121172539/121430679 (Hg38)
End
121172539/121430679 (Hg38)
Location type
Intronic
Target gene
LOC107985194
Nearest miRNA
hsa-mir-101-1/Upstream/4335951; hsa-mir-1182/Downstream/24419908;
Nearest TSS
ENST00000473358/Upstream/17960; ENST00000443018/Downstream/79704;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/33482, chr1-CpG: 75/Downstream/88380
Upstream sequence
CACAGCTagaggccgctgctgtcctggcaagggcataggcctgggtataaggcaggcttgagtctgaagccaggctccactatttgccagcATAGAGGAC
Downstream sequence
CAAGAAGGAACAATGTCACTTGGTAAAACTGAAACTGGTGCTAACAGGGATCAACATAAATCAGGGTGATTCACAGTCTTCCCAGAAACACCCAACTTGA
Reference
Hu, Z., et al. Genome-wide profiling of HPV integration in cervical cancer identifies clustered genomic hot spots and a potential microhomology-mediated integration mechanism. Nat Genet,2015, 47(2): 158-163.
Curate