Basic Information
VIS ID
TVIS20002258
Fusion event
HPV-LINC02755 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Not given
Quality evaluation
Normal
Reported year
2015
PubMed ID
25581428
Virus Sequence
Virus name
HPV
Subtype
HPV16
Reference genome
NC_001526.2
Host Sequence
Chromosome
chr11
Cytoband
p14.1
Reference genome
GRCh37/hg19
Start
29506396/29484849 (Hg38)
End
29506396/29484849 (Hg38)
Location type
Intronic
Target gene
LINC02755
Nearest miRNA
hsa-mir-210/Upstream/1007301; hsa-let-7a-2/Downstream/5456988;
Nearest TSS
ENST00000527297/Upstream/39362; ENST00000530389/Downstream/34227;
Nearest CpG islands
None/Target, chr11-CpG: 30/Upstream/1374175, chr11-CpG: 25/Downstream/531276
Upstream sequence
aggcatggtgccatgcacctgtagtcctagctacttgagaagctgagtgggaggatcgcttgagtccagggaattgagactgcagtgagctgtgattgca
Downstream sequence
cccctgcactccagcctgggtgacagaatgagacactgtctcaaaaaaaaaaaaaaaaGTATTCTGTAGAAATAGATTCAGAAATGCATAAAAATACATA
Reference
Hu, Z., et al. Genome-wide profiling of HPV integration in cervical cancer identifies clustered genomic hot spots and a potential microhomology-mediated integration mechanism. Nat Genet,2015, 47(2): 158-163.
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