Basic Information
VIS ID
TVIS20002343
Fusion event
HPV-chr1:p11.2 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Not given
Quality evaluation
Normal
Reported year
2015
PubMed ID
25581428
Virus Sequence
Virus name
HPV
Subtype
HPV16
Reference genome
NC_001526.2
Host Sequence
Chromosome
chr1
Cytoband
p11.2
Reference genome
GRCh37/hg19
Start
120922847/143887872 (Hg38)
End
120922847/143887872 (Hg38)
Fragile sites / regions
FRA1F
Nearest miRNA
hsa-mir-101-1/Upstream/26793144; hsa-mir-1182/Downstream/1962715;
Nearest TSS
ENST00000473358/Upstream/2796; ENST00000444624/Downstream/17615;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/2383, chr1-CpG: 42/Downstream/16377
Nearby gene
FCGR1CP(-4139) ;
Upstream sequence
acaggtaatttataaagaaaagaggtttatttcactcacaatttttcaggctgggaagttcaagggcataggcctgacttctggcaagagcttttgtgct
Downstream sequence
gcattatcacacggtggagaatctcaaagacgaagcagacaggtgtgaagacatcacatggcaagacaggatgcaagagagtgaaaccgaagaggccaga
Reference
Hu, Z., et al. Genome-wide profiling of HPV integration in cervical cancer identifies clustered genomic hot spots and a potential microhomology-mediated integration mechanism. Nat Genet,2015, 47(2): 158-163.
Curate