Basic Information
VIS ID
TVIS20002347
Fusion event
HPV-ZMIZ1-AS1 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Not given
Quality evaluation
Normal
Reported year
2015
PubMed ID
25581428
Virus Sequence
Virus name
HPV
Subtype
HPV16
Reference genome
NC_001526.2
Host Sequence
Chromosome
chr10
Cytoband
q22.3
Reference genome
GRCh37/hg19
Start
80753281/78993524 (Hg38)
End
80753281/78993524 (Hg38)
Location type
Intronic
Fragile sites / regions
FRA10D
Target gene
ZMIZ1-AS1
Nearest miRNA
hsa-mir-1265/Upstream/3440971; hsa-mir-107/Downstream/7271170;
Nearest TSS
ENST00000439456/Upstream/31130; ENST00000472035/Downstream/10279;
Nearest CpG islands
None/Target, chr10-CpG: 68/Upstream/19268, chr10-CpG: 270/Downstream/73483
Upstream sequence
tagaaacagtgaagttggaagttctttcaaggtaagaaggggatgggaaataaagtgttagctggaagggaacgtggagctggggaagaCCTGAGCATGT
Downstream sequence
TGAAATGCTTCCTGTGCTCGTGGATTCCACATCTTTGTTTCATAAATTGGGAAGGCAGTCTGTGTCAGGCTCTCTGGTGGCTTTGGGATGGGAAAAACTC
Reference
Hu, Z., et al. Genome-wide profiling of HPV integration in cervical cancer identifies clustered genomic hot spots and a potential microhomology-mediated integration mechanism. Nat Genet,2015, 47(2): 158-163.
Curate