Basic Information
VIS ID
TVIS20002349
Fusion event
HPV-LOC105376626 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Not given
Quality evaluation
Normal
Reported year
2015
PubMed ID
25581428
Virus Sequence
Virus name
HPV
Subtype
HPV16
Reference genome
NC_001526.2
Host Sequence
Chromosome
chr11
Cytoband
p13
Reference genome
GRCh37/hg19
Start
35042875/35021328 (Hg38)
End
35042875/35021328 (Hg38)
Location type
Intronic
Fragile sites / regions
FRA11E
Target gene
LOC105376626
Nearest miRNA
hsa-mir-1343/Upstream/79408; hsa-let-7a-2/Downstream/988770;
Nearest TSS
ENST00000527297/Upstream/36695; ENST00000526025/Downstream/116398;
Nearest CpG islands
None/Target, chr11-CpG: 30/Upstream/104495, chr11-CpG: 53/Downstream/117500
Upstream sequence
tttaaccagagccaattgcacGGGGATTTGTGTTGCCCACTTCAGTGTCCTTGGGCTATTTCCTTTCTGGTTTGCCTGGTCTTGGCTAAAAGTTCTGGAA
Downstream sequence
TCACTTCCCAGGAAACATTAAACTTTCTCTGCCATATATGTTCATGCTCACAACTCCTTAGAGTTTGACAAATTGTTTCAGTTCCCACCAAAGCCAGCTT
Reference
Hu, Z., et al. Genome-wide profiling of HPV integration in cervical cancer identifies clustered genomic hot spots and a potential microhomology-mediated integration mechanism. Nat Genet,2015, 47(2): 158-163.
Curate