Basic Information
VIS ID
TVIS20002443
Fusion event
HPV-MS4A6A integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Not given
Quality evaluation
Normal
Reported year
2015
PubMed ID
25581428
Virus Sequence
Virus name
HPV
Subtype
HPV16
Reference genome
NC_001526.2
Host Sequence
Chromosome
chr11
Cytoband
q12.2
Reference genome
GRCh37/hg19
Start
59947477/60180004 (Hg38)
End
59947477/60180004 (Hg38)
Location type
Intronic
Target gene
MS4A6A
Nearest miRNA
hsa-mir-129-2/Upstream/584846; hsa-let-7a-2/Downstream/29067;
Nearest TSS
ENST00000527297/Upstream/39; ENST00000529950/Downstream/1662;
Nearest CpG islands
None/Target, chr11-CpG: 30/Upstream/281620, chr11-CpG: 21/Downstream/335306
Upstream sequence
ATGGACTTGGACATCCTGTCTTTTCCAGAAAAATTTAAGAGATGCCATCCATTTTCTATGTGTGAGGATGGGCGAGCAGGTCTCAAGATGATCAGTGATG
Downstream sequence
TTCAGAAGTTGCACAGAGGAATTCAAGGGGGATATGAAGACAAAGTAAAACATGCTTGGATTGAGGAAAATGCATGTTTACAAGGGGAGATGTACAATAG
Reference
Hu, Z., et al. Genome-wide profiling of HPV integration in cervical cancer identifies clustered genomic hot spots and a potential microhomology-mediated integration mechanism. Nat Genet,2015, 47(2): 158-163.
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