Basic Information
VIS ID
TVIS20002499
Fusion event
HPV-HS3ST4 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Not given
Quality evaluation
Normal
Reported year
2015
PubMed ID
25581428
Virus Sequence
Virus name
HPV
Subtype
HPV16
Reference genome
NC_001526.2
Host Sequence
Chromosome
chr16
Cytoband
p12.1
Reference genome
GRCh37/hg19
Start
25792328/25781007 (Hg38)
End
25792328/25781007 (Hg38)
Location type
Intronic
Fragile sites / regions
FRA16E
Target gene
HS3ST4
Nearest miRNA
hsa-mir-1225/Upstream/1577776; hsa-mir-11401/Downstream/244230;
Nearest TSS
ENST00000527434/Upstream/88981; ENST00000475436/Downstream/105739;
Nearest CpG islands
None/Target, chr16-CpG: 29/Upstream/87697, chr16-CpG: 34/Downstream/1328683
Upstream sequence
CTGCGTCACTCCAGGACTGGAGTGGGCACAGGGGAACTCGGGCCCGATCTCAGCCACAGCTCTTCCTCCAAGAAGACCCCACATGCATTCTGTGCCCCTC
Downstream sequence
aataattaaaatatggaagcctgtgcaattaccaagactttggacttggtttattgggcttgcatgcaacatacagggcagcttgttgttataaaaggga
Reference
Hu, Z., et al. Genome-wide profiling of HPV integration in cervical cancer identifies clustered genomic hot spots and a potential microhomology-mediated integration mechanism. Nat Genet,2015, 47(2): 158-163.
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