Basic Information
VIS ID
TVIS20002500
Fusion event
HPV-TLCD3B integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Not given
Quality evaluation
Normal
Reported year
2015
PubMed ID
25581428
Virus Sequence
Virus name
HPV
Subtype
HPV16
Reference genome
NC_001526.2
Host Sequence
Chromosome
chr16
Cytoband
p11.2
Reference genome
GRCh37/hg19
Start
30053302/30041981 (Hg38)
End
30053302/30041981 (Hg38)
Location type
Intronic
Target gene
TLCD3B
Nearest miRNA
hsa-mir-1225/Upstream/442716; hsa-mir-11401/Downstream/461938;
Nearest TSS
ENST00000527434/Upstream/5451; ENST00000566280/Downstream/10942;
Nearest CpG islands
None/Target, chr16-CpG: 29/Upstream/20171, chr16-CpG: 52/Downstream/10898
Upstream sequence
gttgaaaattctggaaggccccactgacttaccggtacctattcagtagtagaaggctggccccacacccccaggaagttgcaaaacacagttgcacatt
Downstream sequence
AGAGcagtgtttctcaatttttctttcattattgttcccctaaggagccctttttacacttttttttctaatcgctgcctatcacgaaagtttaataaca
Reference
Hu, Z., et al. Genome-wide profiling of HPV integration in cervical cancer identifies clustered genomic hot spots and a potential microhomology-mediated integration mechanism. Nat Genet,2015, 47(2): 158-163.
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