Basic Information
VIS ID
TVIS20002633
Fusion event
HPV-LINC01863 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Not given
Quality evaluation
Normal
Reported year
2015
PubMed ID
25581428
Virus Sequence
Virus name
HPV
Subtype
HPV16
Reference genome
NC_001526.2
Host Sequence
Chromosome
chr5
Cytoband
q35.2
Reference genome
GRCh37/hg19
Start
173073535/173646532 (Hg38)
End
173073535/173646532 (Hg38)
Location type
Intronic
Fragile sites / regions
FRA5G
Target gene
LINC01863
Nearest miRNA
hsa-mir-10397/Upstream/298996; hsa-mir-1229/Downstream/1105202;
Nearest TSS
ENST00000502646/Upstream/4013; ENST00000521373/Downstream/42927;
Nearest CpG islands
None/Target, chr5-CpG: 87/Upstream/29640, chr5-CpG: 23/Downstream/241396
Upstream sequence
GTTTTATCCTTGTGACAAGGACCTAAAACTGAGCATCAACAGCAGCGGTTGAAAGAGAAGCAAACAAAAGTCAGTGCCATATAGAGGTAACGTGCAGCAT
Downstream sequence
gtgtctctgcccagtggaggaacagctccttgccagaatggattccatgaagaccctgcttctcgcgtcactagtgcccatgctgatgtcctgagagggg
Reference
Hu, Z., et al. Genome-wide profiling of HPV integration in cervical cancer identifies clustered genomic hot spots and a potential microhomology-mediated integration mechanism. Nat Genet,2015, 47(2): 158-163.
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