Basic Information
VIS ID
TVIS20002662
Fusion event
HPV-LOC105375284 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Not given
Quality evaluation
Normal
Reported year
2015
PubMed ID
25581428
Virus Sequence
Virus name
HPV
Subtype
HPV16
Reference genome
NC_001526.2
Host Sequence
Chromosome
chr7
Cytoband
p11.2
Reference genome
GRCh37/hg19
Start
55064998/54997305 (Hg38)
End
55064998/54997305 (Hg38)
Location type
Intronic
Fragile sites / regions
FRA7A
Target gene
LOC105375284
Nearest miRNA
hsa-mir-1183/Upstream/10115505; hsa-mir-10399/Downstream/1958480;
Nearest TSS
ENST00000635602/Upstream/237331; ENST00000459688/Downstream/21716;
Nearest CpG islands
None/Target, chr7-CpG: 39/Upstream/63909, chr7-CpG: 31/Downstream/7268
Upstream sequence
taaagaatcagacacaaaaaaaatcacttgtttttcttgatttcactttttactagagatcctaaccaatacagttagacaaaaagaacaaatacaccca
Downstream sequence
gactttctctctaaggggccaactagtaaatcttctagaccatgtgggccatgcggtctctgttgcgactcctcagctctgttatcctagcatgaaagca
Reference
Hu, Z., et al. Genome-wide profiling of HPV integration in cervical cancer identifies clustered genomic hot spots and a potential microhomology-mediated integration mechanism. Nat Genet,2015, 47(2): 158-163.
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