Basic Information
VIS ID
TVIS20002673
Fusion event
HPV-LINC-PINT integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Not given
Quality evaluation
Normal
Reported year
2015
PubMed ID
25581428
Virus Sequence
Virus name
HPV
Subtype
HPV16
Reference genome
NC_001526.2
Host Sequence
Chromosome
chr7
Cytoband
q32.3
Reference genome
GRCh37/hg19
Start
130576691/130891932 (Hg38)
End
130576691/130891932 (Hg38)
Location type
Intronic
Fragile sites / regions
FRA7H
Target gene
LINC-PINT
Nearest miRNA
hsa-mir-10525/Upstream/14393; hsa-mir-10399/Downstream/2142928;
Nearest TSS
ENST00000635602/Upstream/38212; ENST00000608412/Downstream/21244;
Nearest CpG islands
None/Target, chr7-CpG: 39/Upstream/157556, chr7-CpG: 215/Downstream/213667
Nearest cancer related gene
LINC-PINT(TSG, No orient, 0)
Upstream sequence
TCGGTAACTCCGCATTTCATGTGATCATTACCTGCATTACTCACATGAAATCtcactgacctggattgtaacaacctttccacatgtcttcctcagcagt
Downstream sequence
AGttaagaaaatgtggcacatatacaccatggaatactatgcagccataaaaaatgatgagttcatgtcctttgtagggacatggatgaaattggaaacc
Reference
Hu, Z., et al. Genome-wide profiling of HPV integration in cervical cancer identifies clustered genomic hot spots and a potential microhomology-mediated integration mechanism. Nat Genet,2015, 47(2): 158-163.
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