Basic Information
VIS ID
TVIS20002752
Fusion event
HPV-chr1:p34.3 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Squamous-cell carcinoma (SCC)
Quality evaluation
Normal
Reported year
2015
PubMed ID
25581428
Virus Sequence
Virus name
HPV
Subtype
HPV16
Reference genome
NC_001526.2
Host Sequence
Chromosome
chr1
Cytoband
p34.3
Reference genome
GRCh37/hg19
Start
34690712/34225111 (Hg38)
End
34690712/34225111 (Hg38)
Nearest miRNA
hsa-mir-12136/Upstream/892619; hsa-mir-101-1/Downstream/444488;
Nearest TSS
ENST00000473358/Upstream/47441; ENST00000338513/Downstream/529936;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/47688, chr1-CpG: 22/Downstream/536316
Nearby gene
C1orf94(-5980) ;
Upstream sequence
TGTTAGCATTTGAGATTTCCTTTTAAAATGTGACCAGACATTCATATACATGTGCAGACTTTCATTTTAATCAGCAACATGCAAATTGCATATTCATCTG
Downstream sequence
GATAGACATAGGGCAGGCACTGTTCATAGAGATACGGCTGCACATTACAGGCACAATTCTGGTGAAAGGAAATCTTTTTTTTTAAGTCCTGGAGGTAAAA
Reference
Hu, Z., et al. Genome-wide profiling of HPV integration in cervical cancer identifies clustered genomic hot spots and a potential microhomology-mediated integration mechanism. Nat Genet,2015, 47(2): 158-163.
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