Basic Information
VIS ID
TVIS20002757
Fusion event
HPV-chr1:p13.1 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Squamous-cell carcinoma (SCC)
Quality evaluation
Normal
Reported year
2015
PubMed ID
25581428
Virus Sequence
Virus name
HPV
Subtype
HPV16
Reference genome
NC_001526.2
Host Sequence
Chromosome
chr1
Cytoband
p13.1
Reference genome
GRCh37/hg19
Start
117024687/116482065 (Hg38)
End
117024687/116482065 (Hg38)
Nearest miRNA
hsa-mir-101-1/Upstream/3599936; hsa-mir-1182/Downstream/77959;
Nearest TSS
ENST00000473358/Upstream/3223; ENST00000624685/Downstream/17147;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/63145, chr1-CpG: 30/Downstream/52355
Nearby gene
LINC01762(-3239) ; LOC112268235(+2627) ;
Upstream sequence
gcacaatcatagctcactgcagtctcaaactcctgggctccagcgatcctcctgcctcagcctcacaggtagctgggactacaggcacgaaccaccacac
Downstream sequence
ctctctaattttttaaaaaaatttttggtagagatggggtcttgctatgttgcccaggctggtctcaaactcatggcctcaagcaatcatccctccttgg
Reference
Hu, Z., et al. Genome-wide profiling of HPV integration in cervical cancer identifies clustered genomic hot spots and a potential microhomology-mediated integration mechanism. Nat Genet,2015, 47(2): 158-163.
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