Basic Information
VIS ID
TVIS20002764
Fusion event
HPV-chr10:q26.12 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Squamous-cell carcinoma (SCC)
Quality evaluation
Normal
Reported year
2015
PubMed ID
25581428
Virus Sequence
Virus name
HPV
Subtype
HPV16
Reference genome
NC_001526.2
Host Sequence
Chromosome
chr10
Cytoband
q26.12
Reference genome
GRCh37/hg19
Start
122996890/121237376 (Hg38)
End
122996890/121237376 (Hg38)
Fragile sites / regions
FRA10D ; FRA10F ; FRA10A ; FRA10B
Nearest miRNA
hsa-mir-107/Upstream/1278784; hsa-mir-202/Downstream/1179589;
Nearest TSS
ENST00000439456/Upstream/58676; ENST00000447943/Downstream/243109;
Nearest CpG islands
None/Target, chr10-CpG: 68/Upstream/257498, chr10-CpG: 185/Downstream/359726
Upstream sequence
gtaggtatgtaggtggattagtaggtgcatttgtaggtagctatgcatgtagatacctatgtaggtatgtaggtggatctgtaggtgtacttggaggtaa
Downstream sequence
gtgtgcaggtaggtatttatgtaggtatgtaggtggatttgtaggtgtacttggaggtaggtacctatgtaggtatgcaggtagatatgtaggtgcactt
Reference
Hu, Z., et al. Genome-wide profiling of HPV integration in cervical cancer identifies clustered genomic hot spots and a potential microhomology-mediated integration mechanism. Nat Genet,2015, 47(2): 158-163.
Curate